Can we someday transplant the brain from one body to another?

The thing is that transplant a head straight from one body to another is not possible because the immune defense destroys the transplant. Also, the spinal cord is hard to connect. And because the spinal cord cannot make them grow together, because immune defense destroys those cells. Making a working head transplant is not possible. The immune system is the thing that made Ilya Ivanovich Ivanov's (1870-1932) experiments in the 1920s impossible.

But Ilya Ivanovich Ivanov was a pathfinder. He made the dog's head live in the machine for a couple of days. And that thing can use for making surgical operations on the body. 

Then that body can reconnect with the own body of the person. The only thing is how to connect the spinal cord. If the person has large-scale injuries the head can remove. And then medical staff can cure the body and remove things, like some poisons. The head can connect to the heart-lung machine when the operators work with the body. The idea is that separation of the head denies the poison transfer to brain tissue. 

One version of the brain transplant is the process where researchers destroy the person's immune system. And that means the immune system will not destroy the transplant. But the person must use a space suit while being outside. And that person must live in a house that looks like a space station. If one single organism slips into that house or base that causes death immediately. 

But then we must realize that Ivanov did not know about genetics and immunology. During his lifetime nobody even knew the DNA or at least its role as genetic code in living organisms. Ivanov couldn't create synthetic DNA or RNA bites. And there is a possibility that large-scale genetic transplants can be made by using synthetic retroviruses. In this case, the laboratory creates synthetic RNA bites by splitting the DNA. Then those RNA bites will inject into the cells. 

Or some cells can transform to create synthetic RNA-retroviruses. Those viruses can have similar core antigens and structures to the AIDS virus. But the genetic material that is connected to the cell's genomes could involve instructions to make neurons. The thing is that those viruses can inject into any organism on this planet. 

There are two possibilities to make a brain transplant. 

*Chancing the entire head.

*Changing only brains. 

If we want to change heads between persons, researchers must use highly effective immune depressants. And the tissue typing must make very careful that the body and head are close to each other as possible. But that requires the body. So in this case the problem is how to get a younger body for that operation. The tissue antigens must be as near to each other as possible. 

Or genome therapy can change the core antigens of the head. In that case, the tissues in the head are turned to similar. With the body where that head will transfer. But that kind of immune therapy is possible in the future. Today we cannot do that thing. The idea is that the artificial virus that is made by using the DNA of receiving body will inject into the head. And then that virus transfers the antigens of the cells. 

And that genome transfer must make the antigens of the head and body identical. If that is successful. A head transplant is possible. There is the possibility that the spinal cord will put two microchips that connect the broken neural tracks.

But what if researchers are transplanting only the brain?

There are also two ways to make the neuron transplant between the brain. 

*Real neurons are used for neuron transplant. 

*Or the EEG or the skills that the donor's neurons are involved. Will transplant to the new body. 

There is a vision of the future.

The lab-grown human neurons were transplanted into a rat's brain. That thing causes visions. That in the future is possible. Researchers can make rats with customized genomes. Those rats can use to create customized stem cells or neurons. In that case, the synthetic RNA from the receiver's body can transfer to the rats. And that makes it possible that they can create stem cells. That is fitting perfectly into people who will receive them. 

Or before a person bor. Medical staff takes stem cells from the fetus and stores them in liquid nitrogen. Then those stem cells can multiply by multiplying their genome in the laboratory. And then inject them into some other cells whose own genome was removed by researchers. 

Genetically engineered rats can use to create neurons with the same antigens as the receiving body. In that case, the genetic material of the rats can manipulate the tissue types of those rats to be identical to the receiving body. The thing is that nanotechnology along with artificial intelligence and new observation tools are increasing our knowledge and capacity in genetic engineering. 

Then those lab-grown neurons will inject into the damaged brain. The problem is that the skills that are stored in those damaged neurons must somehow restore. Those skills can transfer to those lab-grown cells. But that requires accurate data on the lost memories. Or the system that transfers memories to those cells must use synthetic memories. 

Theoretically, brain transfer is not as difficult as people might think. The problem is how to deny immune cells to destroy those cells. There is the possibility that the stem cells that are just starting to specialize would inject into the person's brain. In some other visions, the gel that is made by using neurons can inject into the brain or head. 

And then those neurons would travel to the right points. But that requires that those neuron's antigens are not launching the immune system. In some visions, researchers make neuron transplant by using cloned neurons. That is taken from receiving body. Then the needed information will load onto those cells by using electric stress. 

In that case, the needed thing is stem cells there is transplanted the DNA of the neurons. And one vision is this. 

Researchers can make this genome transfer to cancer cells. That is quite similar to stem cells. 

The lab-grown human neurons made a working neural network in the rat's brain. That thing shows that neurons can transfer between species. 

This thing means that neurons themselves can transfer at least between species. So if human neurons can transfer to rats the opposite transplant is also possible. There is the possibility that in the future. There are lab-grown rat neurons that genetically transform to fit the receiving body. 

https://drchandrilchugh.com/blog/is-brain-transplantation-possible/

https://ec.europa.eu/research-and-innovation/en/projects/success-stories/all/lab-grown-neurons-pave-way-precision-medicine

https://www.news-medical.net/life-sciences/Lab-Grown-Neurons.aspx

https://www.quantamagazine.org/lab-grown-human-cells-form-working-circuits-in-rat-brains-20221012/

https://en.wikipedia.org/wiki/Brain_transplant

https://en.wikipedia.org/wiki/Humanzee

https://en.wikipedia.org/wiki/Ilya_Ivanov

There are videos of Ivanov's experiments. I don't put them in here.  But you can find them on YouTube. Use words "ilya ivanovich ivanov". 

https://designandinnovationtales.blogspot.com/

New research can give fundamental tools for autoimmune diseases and genome transfer.

What if researchers can someday switch the immune system on and off? Maybe that thing is possible in the future. 

Researchers are found a "switch off" button in the immune system. This "switch off" button deactivates the MR1 (MHC class I-related molecule) that activates the immune system. If the immune activator is turned off or deactivated. That thing makes it possible to make an organ transplant. Deactivation of the immune system can also decrease the HIV-virus infection. 

The idea is that the immune cells would not eat HIV viruses. And the antigens that could resist that virus can produce in laboratories.

'During this therapy the person must be in an absolute sterile room, where is no biological material. The idea is that the immune system will not eat those viruses. And decrease their ability to produce descendants. Or maybe, even if that kind of thing cannot use against HIV it can help to make a successful organ transplant. 

When the immune system is that will help the body can accept the organ. The biggest problem in organ transfer operations is the immune system which destroys organs that have the wrong antigens. 

In cases where the immune system operates wrong like rheumatism, there is the possibility to reprogram immune cells to deny overreaction. That requires the ability to reboot the immune system. 

Even if the researchers can adjust when the immune system is on, and when it's off that will be the fundamental thing.

That makes it possible to give a new type of medicine. The problem with some organic molecules is that the immune system destroys them immediately. That means they will get in the wrong cells. 

Same way if the bio-manipulated bacteria wanted to use to remove things like plaque from veins the problem is that the immune system destroys those bacteria. So the bacteria can release in the veins while the immune system is switched off. And when they have done their duty, the immune system can activate again. 

The new RNA tool can help to give successful genome therapy. The ability to make cells illuminate helps researchers to see how genome therapy advances in the cell group. 

The RNA-based tool that can make brain circuits illuminate and edit individual cells can have multiple uses in medicines. The RNA tool can make it possible to transfer genomes to cells. And if we think about organ transplants the RNA tool can use to change the molecular structure of the membrane proteins of those cells. 

https://scitechdaily.com/groundbreaking-research-exposes-immune-systems-off-button/

https://scitechdaily.com/new-rna-tool-can-illuminate-brain-circuits-and-edit-specific-cells/

Image:) https://scitechdaily.com/groundbreaking-research-exposes-immune-systems-off-button/

Nanotechnology and the immune system

Picture I

https://crisisofdemocracticstates.blogspot.com/

Kimmo Huosionmaa

Nanotechnology and immune defense are the combinations, what people don't usually think that would sometimes save the life. When we are thinking the vaccine of tomorrow, we might think that inside human body would be injected with the nanorobots, what would transfer the antigene of the organism straight to the stem cells, where the immune cells are forming, and that might increase the power of the vaccine.


The term "antigen" means the part of the mantle of the targeted organism to the stem cells, and that opens new ways to give the vaccine. One of the most modern ideas is that those nanorobots, what might look like small crayfish would catch the organism from blood, and transfer it straight to the place, where the cells of the immune defense are forming.


Also if there are enough those machines, they can also destroy bacteria and tumors by closing the blood veins in there by using carbon. In this case, the carbon would be injected into the veins with the nanomachines, what would carry them in the wanted position.  Or they can cut the mantle of the bacteria open, what would destroy it immediately.


The question is, how the nanomachines would do that thing? They can operate under the command of the computer, what is outside the body, and communicate with that computer by using radio signals. And the radio waves can also transfer electricity for those small robots. The position of nanomachines in the body can get from RFID sensors, what allows the computer to control each of them independently. And that would give them the opportunity to make surgical operations inside the human body. Those small robots can slip into the body by using sweat gland's channel, what the body uses when it removes sweat.


Those robots can be very lethal if they are in the wrong hands. If that small robot would take the part of the targeted person's cells, it would cause the terrible immune reaction, that could exterminate that person. After that, the nanorobot can slip off the body, and it would not leave any trace of its existence. Those extreme small robots can be delivered to the targets department by using nano bugs, and they can be controlled by the relay systems, what are installed in nanobugs or quadcopters. They can be used in special forces operations.


And is some scenarios the agents of DEA or other anti-crime offices have this kind of robot in the body, and if they are in trouble the systems, what is telling about the condition of the body would release that nanotechnological crayfish. This crayfish would slip in the bodies of the hostage takers, and after that, they would be facing the death, what is the most unwilling, that human mind can imagine. Those cells, what is used to turn the immune system can collect from the target's own body. And this makes the nanorobot the perfect weapon.

Picture I

http://en.oicnanocurcumin.vn/upload/files/new%20technology/medical1.jpg

Theories about the places like "The Strid" and when the immune system starts to act against own body.

http://www.choson.webd.pl/Amatorska/wbetag07.jpg

https://kimmontaidearvioita.blogspot.com/

Kimmo Huosionmaa

There are many theories about the places like "The Strid", and one of them is that there live very strange bacteria in the water. The bacteria would form the chemicals, that seems the poison of the sea anemones. And before any organic material would touch that bacteria it is harmless. This could be the reason, that there is no chemical reaction in that water. In the normal situation, those bacteria would not create any poison.


But then when that bacteria is facing the antigenome of the living cells, that would create the chemicals what are causing the concatenation of those bacteria, when they become dangerous. When we are talking about people, who just die, without explanation, we might think that there is the possibility, that there would be some kind of virus, that would destroy mitochondria.


This would not seem in the autopsy, but if the mitochondria would be destroyed, a human's ability to create power in the cells would end. Or the thing could be some kind of formed malaria amoeba, what would destroy those mitochondria. In some scenarios, the formed amoeba would take the place of mitochondria and cause that the cell loses the energy supply. But there is another possibility that this kind of situation happens.


This hypothesis would caused in the situation, that the immune defense system would take wrong antigens to the stem cells. This is how the immune resistance is forming, and if the antigen is from the own body of the human, the immune cells would attack against that cell group. That means if the cell group is forming the veins, the immune cells would cause that all the veins would be destroyed. This would cause the death immediately.