The cancer cell's ability to fix its DNA makes it possible to create genome therapy against cancer and aging.

Researchers found how cancer cells are fixing their DNA damage. That gives great opportunities for cancer treatment. But what if that ability can transfer to normal cells? That thing makes those cells able the resist things like aging or cancer.

Reprogramming cells is one of the possibilities to remove at least some cancer or other diseases from the human race. The ability to transfer synthetic DNA to cells makes them produce new DNA and remove the old. In nature, the retrovirus is making that thing all the time. So synthetic retroviral can make this thing possible. In that case, the retrovirus virus will just slip the new genome in the form of the RNA in the human cells.

That means the synthetic DNA can slip into the cells and drive through cell organelles. Or actually, the RNA will just take the cell organelles under the control and programs them to create the new DNA for the cells.

That DNA can involve orders to destroy the old DNA and replace it with new DNA that those cell organs create. The process will look like mitosis. But the old DNA will just be destroyed in this process and replaced by using the new DNA. Then the DNA must remove the sequences from it that make that replacement process possible.

A cancer cell's ability to fix its DNA is the thing that denies the effect of a medicine. The same ability that makes cancer cells fix the DNA is the thing that can use to reprogram cells. That thing can make it possible. That cancer can be removed, from the human race. In that case, the researchers remove the DNA sequence that causes cancer from the DNA. Or researchers can replace it by using wealthy DNA.

Replacement of the damaged DNA is easy to make in the morula-level embryos. The researchers must just make the wealthy DNA and then suck the damaged DNA out from the morula. Then they can inject wealthy DNA into that embryo. That thing is quite easy to make. Researchers must just take the morula out from the mother's body for a moment, change the DNA and then put the morula back.

Reprogramming cells means that the young or not damaged DNA will transfer to cells. If the DNA in the nucleus of the cells can replace with no-damaged DNA that thing can make a person theoretically immortal. The reason for aging is damaged DNA. If we want to make a person immortal we must also change mitochondria from the cells.

Researchers are making tests with old mice who are got the blood of young mice. And that young blood made them younger. The young blood caused the situation that the cells transfer the young DNA to the nucleus of the cells.

There is also the possibility that young blood is causing the renewal of the mitochondria. The effect of the blood transplant is confirmed. But the point is does that new blood affect the nucleus of the cells, or does that thing affect mitochondria? The problem with DNA reprogramming is that there are a lot of cells in the human body.

If somebody wants to change the DNA in the nucleus of the cells there is one possibility. That possibility is the genetically engineered bacteria. In that case, the research program bacteria to create the new DNA. And then the bacteria will just pull the old DNA out and replace it with new fresh DNA.

Researchers can make that thing by using synthetic DNA plasmids. The fresh DNA can produce by using cells that are taken from a person just after birth. Or the DNA that is taken straight after birth can transfer to cells. And then the cell cultures can use to create the DNA. Some laboratories are researching the possibility to reprogram cells. Genetic engineering opens new roads for wealthy humans.

The DNA-controlled nanomachines are giving information. That is useful for use in the control of artificial bacteria. The creation of artificial bacteria allows making a new type of large-scale genome therapy. In those models, the bacteria that is injected into the human body will create new DNA and changes the DNA from the nucleus of the cells. And as I wrote before the mitochondria must also renew.

https://www.science.org/content/article/young-blood-renews-old-mice

https://scitechdaily.com/a-new-way-that-cancer-cells-can-repair-dna-damage-has-been-discovered/

https://yle.fi/uutiset/3-12474217

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