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New research can give fundamental tools for autoimmune diseases and genome transfer.



What if researchers can someday switch the immune system on and off? Maybe that thing is possible in the future. 

Researchers are found a "switch off" button in the immune system. This "switch off" button deactivates the MR1 (MHC class I-related molecule) that activates the immune system. If the immune activator is turned off or deactivated. That thing makes it possible to make an organ transplant. Deactivation of the immune system can also decrease the HIV-virus infection. 

The idea is that the immune cells would not eat HIV viruses. And the antigens that could resist that virus can produce in laboratories.

'During this therapy the person must be in an absolute sterile room, where is no biological material. The idea is that the immune system will not eat those viruses. And decrease their ability to produce descendants. Or maybe, even if that kind of thing cannot use against HIV it can help to make a successful organ transplant. 

When the immune system is that will help the body can accept the organ. The biggest problem in organ transfer operations is the immune system which destroys organs that have the wrong antigens. 

In cases where the immune system operates wrong like rheumatism, there is the possibility to reprogram immune cells to deny overreaction. That requires the ability to reboot the immune system. 


Even if the researchers can adjust when the immune system is on, and when it's off that will be the fundamental thing.


That makes it possible to give a new type of medicine. The problem with some organic molecules is that the immune system destroys them immediately. That means they will get in the wrong cells. 

Same way if the bio-manipulated bacteria wanted to use to remove things like plaque from veins the problem is that the immune system destroys those bacteria. So the bacteria can release in the veins while the immune system is switched off. And when they have done their duty, the immune system can activate again. 

The new RNA tool can help to give successful genome therapy. The ability to make cells illuminate helps researchers to see how genome therapy advances in the cell group. 

The RNA-based tool that can make brain circuits illuminate and edit individual cells can have multiple uses in medicines. The RNA tool can make it possible to transfer genomes to cells. And if we think about organ transplants the RNA tool can use to change the molecular structure of the membrane proteins of those cells. 

https://scitechdaily.com/groundbreaking-research-exposes-immune-systems-off-button/


https://scitechdaily.com/new-rna-tool-can-illuminate-brain-circuits-and-edit-specific-cells/


Image:) https://scitechdaily.com/groundbreaking-research-exposes-immune-systems-off-button/


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