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Can we someday transplant the brain from one body to another?



The thing is that transplant a head straight from one body to another is not possible because the immune defense destroys the transplant. Also, the spinal cord is hard to connect. And because the spinal cord cannot make them grow together, because immune defense destroys those cells. Making a working head transplant is not possible. The immune system is the thing that made Ilya Ivanovich Ivanov's (1870-1932) experiments in the 1920s impossible.

But Ilya Ivanovich Ivanov was a pathfinder. He made the dog's head live in the machine for a couple of days. And that thing can use for making surgical operations on the body. 

Then that body can reconnect with the own body of the person. The only thing is how to connect the spinal cord. If the person has large-scale injuries the head can remove. And then medical staff can cure the body and remove things, like some poisons. The head can connect to the heart-lung machine when the operators work with the body. The idea is that separation of the head denies the poison transfer to brain tissue. 

One version of the brain transplant is the process where researchers destroy the person's immune system. And that means the immune system will not destroy the transplant. But the person must use a space suit while being outside. And that person must live in a house that looks like a space station. If one single organism slips into that house or base that causes death immediately. 

But then we must realize that Ivanov did not know about genetics and immunology. During his lifetime nobody even knew the DNA or at least its role as genetic code in living organisms. Ivanov couldn't create synthetic DNA or RNA bites. And there is a possibility that large-scale genetic transplants can be made by using synthetic retroviruses. In this case, the laboratory creates synthetic RNA bites by splitting the DNA. Then those RNA bites will inject into the cells. 

Or some cells can transform to create synthetic RNA-retroviruses. Those viruses can have similar core antigens and structures to the AIDS virus. But the genetic material that is connected to the cell's genomes could involve instructions to make neurons. The thing is that those viruses can inject into any organism on this planet. 



There are two possibilities to make a brain transplant. 


*Chancing the entire head.


*Changing only brains. 


If we want to change heads between persons, researchers must use highly effective immune depressants. And the tissue typing must make very careful that the body and head are close to each other as possible. But that requires the body. So in this case the problem is how to get a younger body for that operation. The tissue antigens must be as near to each other as possible. 

Or genome therapy can change the core antigens of the head. In that case, the tissues in the head are turned to similar. With the body where that head will transfer. But that kind of immune therapy is possible in the future. Today we cannot do that thing. The idea is that the artificial virus that is made by using the DNA of receiving body will inject into the head. And then that virus transfers the antigens of the cells. 

And that genome transfer must make the antigens of the head and body identical. If that is successful. A head transplant is possible. There is the possibility that the spinal cord will put two microchips that connect the broken neural tracks.


But what if researchers are transplanting only the brain?


There are also two ways to make the neuron transplant between the brain. 


*Real neurons are used for neuron transplant. 


*Or the EEG or the skills that the donor's neurons are involved. Will transplant to the new body. 


There is a vision of the future.


The lab-grown human neurons were transplanted into a rat's brain. That thing causes visions. That in the future is possible. Researchers can make rats with customized genomes. Those rats can use to create customized stem cells or neurons. In that case, the synthetic RNA from the receiver's body can transfer to the rats. And that makes it possible that they can create stem cells. That is fitting perfectly into people who will receive them. 

Or before a person bor. Medical staff takes stem cells from the fetus and stores them in liquid nitrogen. Then those stem cells can multiply by multiplying their genome in the laboratory. And then inject them into some other cells whose own genome was removed by researchers. 

Genetically engineered rats can use to create neurons with the same antigens as the receiving body. In that case, the genetic material of the rats can manipulate the tissue types of those rats to be identical to the receiving body. The thing is that nanotechnology along with artificial intelligence and new observation tools are increasing our knowledge and capacity in genetic engineering. 

Then those lab-grown neurons will inject into the damaged brain. The problem is that the skills that are stored in those damaged neurons must somehow restore. Those skills can transfer to those lab-grown cells. But that requires accurate data on the lost memories. Or the system that transfers memories to those cells must use synthetic memories. 

Theoretically, brain transfer is not as difficult as people might think. The problem is how to deny immune cells to destroy those cells. There is the possibility that the stem cells that are just starting to specialize would inject into the person's brain. In some other visions, the gel that is made by using neurons can inject into the brain or head. 

And then those neurons would travel to the right points. But that requires that those neuron's antigens are not launching the immune system. In some visions, researchers make neuron transplant by using cloned neurons. That is taken from receiving body. Then the needed information will load onto those cells by using electric stress. 

In that case, the needed thing is stem cells there is transplanted the DNA of the neurons. And one vision is this. 

Researchers can make this genome transfer to cancer cells. That is quite similar to stem cells. 

The lab-grown human neurons made a working neural network in the rat's brain. That thing shows that neurons can transfer between species. 

This thing means that neurons themselves can transfer at least between species. So if human neurons can transfer to rats the opposite transplant is also possible. There is the possibility that in the future. There are lab-grown rat neurons that genetically transform to fit the receiving body. 


https://drchandrilchugh.com/blog/is-brain-transplantation-possible/


https://ec.europa.eu/research-and-innovation/en/projects/success-stories/all/lab-grown-neurons-pave-way-precision-medicine


https://www.news-medical.net/life-sciences/Lab-Grown-Neurons.aspx


https://www.quantamagazine.org/lab-grown-human-cells-form-working-circuits-in-rat-brains-20221012/


https://en.wikipedia.org/wiki/Brain_transplant


https://en.wikipedia.org/wiki/Humanzee


https://en.wikipedia.org/wiki/Ilya_Ivanov


There are videos of Ivanov's experiments. I don't put them in here.  But you can find them on YouTube. Use words "ilya ivanovich ivanov". 


https://designandinnovationtales.blogspot.com/

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